STUDIES ON THE SYNTHESIS OF HIPPURIC ACID IN THE ANIMAL ORGANISM. I. THE SYNTHESIS OF HIPPURIC ACID IN RABBITS ON A GLYCOCOLL-FREE DIET
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چکیده
منابع مشابه
Studies on the Synthesis of Hippuric Acid in the Animal Organism
The source of the glycocoll made available for detoxication after the ingestion of benzoic acid or its salts is not known. The possibility that hippuric acid is formed from the glycocoll secreted as glycocholic acid in the bile either in the intestine or in the circulatory system has been suggested. Such a theory would ascribe to the bile an important function. Little experimental evidence in s...
متن کاملStudies in the Synthesis of Hippuric Acid in the Animal Organism. Ii. the Synthesis and Rate of Elimination of Hippuric Acid after Benzoate
The question of the extent of the ability of the human organism to detoxicate benzoic acid by conjugation with glycocoll and elimination as hippuric acid in the urine has frequently been raised. Lewinsk? observed in the urine of men to whom 12 to 20 grams of benzoic acid had been given in small doses during t,he course of twelve hours, neither free benzoic acid nor benzoyl glycuronates. With la...
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ژورنال
عنوان ژورنال: Journal of Biological Chemistry
سال: 1914
ISSN: 0021-9258
DOI: 10.1016/s0021-9258(18)88391-0